Neuronal personalities in central vestibular signal processing

Thursday, December 3rd, 2015, 11:00 am
Elmore Auditorium
2015-16 SEMINAR SERIES: Sascha du Lac, PhD, Johns Hopkins Medicine
Jason Christie, PhD
(561) 972-9000

Event Information

The brain’s remarkable ability to respond rapidly and adaptively to self-motion signals in everyday life relies on signal processing in the vestibular system.  Neurons in the brainstem vestibular nuclei that transform inner ear signals into appropriate motor commands have long been modeled as generic linear operators with little attention to underlying cell biology.   Our studies of intrinsic and synaptic physiology and of differential gene expression indicate, to the contrary, that vestibular nucleus neurons are biophysically specialized for their distinct roles in behavioral signal processing.  Coordinated expression of ion channel genes produces gradient of cell types differentially tuned for precise spike timing vs subthreshold integration.  Vestibular neurons with distinct physiological personalities are thus differentially responsible for rapid initiation vs maintained stability of vestibular behaviors.

This seminar is open to faculty, scientists, and students from Max Planck Florida Institute for Neuroscience (MPFI), Florida Atlantic University (FAU), and the Scripps Research Institute Florida, located on FAU’s John D. MacArthur Campus in Jupiter, Florida. If you belong to an institution outside of the Jupiter campus and would like to attend, please send a request to